Rubella

Rubella and Congenital Rubella Syndrome

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

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All

ATC	Name	B/G	Ingredients	Form	Price
V01AA	DIATER	B	Allergen extracts -	Spray	26,856,672 L.L
C05BX51	DOXIPROCT PLUS	B	Calcium dobesilate - 4%, Dexamethasone acetate - 0.0025%, Lidocaine HCl - 2%	Ointment	489,159 L.L
V01AA	DIATER	B	Allergen extracts -	Spray	34,962,083 L.L
V01AA	DIATER	B	Allergen extracts -	Spray	35,697,531 L.L
V01AA	DIATER	B	Allergen extracts -	Spray	26,856,672 L.L
B05DB	DIANEAL PD4 CYCLER 1.36% GLUCOSE	B	Sodium lactate - 4.48g/l, Magnesium chloride - 0.051g/l, Calcium chloride - 0.184g/l, Sodium chloride - 5.38g/l, Anhydrous glucose - 13.6g/l	Injectable solution	1,150,329 L.L
M01AB55	DIFEN FLEX	G	Diclofenac sodium - 50mg, Pridinol mesylate - 4mg	Tablet, film coated	575,165 L.L
B05DB	DIANEAL PD4 2.27% GLUCOSE	B	Sodium lactate - 4.48g/l, Magnesium chloride - 0.051g/l, Calcium chloride - 0.184g/l, Sodium chloride - 5.38g/l, Anhydrous glucose - 22.7g/l	Injectable solution	1,163,270 L.L
M01AB55	DIFEN FLEX	G	Diclofenac sodium - 75mg, Pridinol mesylate - 2.2mg	Injectable solution	1,131,515 L.L
R05X	DULSANA COUGH	B	Menthol - 0.25mg/5ml, Ammonium chloride - 100mg/5ml, Ephedrine HCl - 4mg/5ml, Carbinoxamine maleate - 2mg/5ml	Syrup	223,974 L.L
B05DB	DIANEAL PD4 CYCLER 2.27% GLUCOSE	B	Sodium lactate - 4.48g/l, Magnesium chloride - 0.051g/l, Calcium chloride - 0.184g/l, Sodium chloride - 5.38g/l, Anhydrous glucose - 22.7g/l	Injectable solution	1,150,329 L.L
C05CA53	DAFLON	B	Hesperidin - 50mg, Diosmin - 450mg	Tablet, film coated	627,574 L.L
M01AB55	DIFEN PLUS	G	Diclofenac potassium - 50mg, Betamethasone - 0.3mg	Tablet, coated	503,941 L.L
R05X	DULSANA MILD	B	Menthol - 0.125mg/5ml, Citric acid - 10mg/5ml, Sodium citrate - 20mg/5ml, Ammonium chloride - 50mg/5ml, Ephedrine HCl - 1.8mg/5ml, Carbinoxamine maleate - 1mg/5ml	Syrup	216,295 L.L
B05DB	DIANEAL PD4 3.86% GLUCOSE	B	Sodium lactate - 4.48g/l, Magnesium chloride - 0.051g/l, Calcium chloride - 0.184g/l, Sodium chloride - 5.38g/l, Anhydrous glucose - 38.6g/l	Injectable solution	1,111,506 L.L
C05CA53	DAFLON	B	Hesperidin - 50mg, Diosmin - 450mg	Tablet, film coated	1,191,988 L.L
M01AB55	DIFEN B12	G	Diclofenac potassium - 50mg, Betamethasone - 0.3mg, Cyanocobalamin - 5mg	Tablet	503,941 L.L
B05DB	DIANEAL PD4 CYCLER 3.86% GLUCOSE	B	Sodium lactate - 4.48g/l, Magnesium chloride - 0.051g/l, Calcium chloride - 0.184g/l, Sodium chloride - 5.38g/l, Anhydrous glucose - 38.6g/l	Injectable solution	1,150,329 L.L
C05CA53	DAFLON	B	Hesperidin - 100mg, Diosmin - 900mg	Tablet, film coated	1,256,493 L.L
M01AB55	DIOXAFLEX B12	G	Diclofenac sodium - 75mg, Betamethasone (sodium phosphate) - 2mg, Hydroxocobalamin sulphate - 10mg	Injectable solution	1,104,639 L.L
D10AF51	DUAC ONCE DAILY	B	Clindamycin (phosphate) - 1%, Benzoyl peroxide - 5%	Gel	1,658,302 L.L
M01AB55	DIOXAFLEX B12	G	Diclofenac sodium - 75mg, Betamethasone (sodium phosphate) - 2mg, Hydroxocobalamin sulphate - 10mg	Injectable solution	620,855 L.L
M01AB55	DIFEN B12	G	Diclofenac sodium - 75mg, Prednisolone sodium phosphate - 10.08mg, Hydroxocobalamin acetate - 10.44mg	Injectable solution	978,317 L.L
N01BB52	DILOCAIN 2%	G	Lidocaine HCl - 20mg/1.7ml, Epinephrine (bitartrate) - 0.0125mg/1.7ml	Injectable solution	2,768,316 L.L
B03BA51	DEPOVEX	B	Aluminium monostearate - 20mg/ml, Cyanocobalamine - 1mg/ml	Injectable oily suspension	423,310 L.L
R06AB54	DRAUDEX	G	Chlorphenamine maleate - 4mg, Phenylephrine - 5mg	Tablet, sugar coated	166,381 L.L
G04CA52	DUTAMSUVITAE	G	Tamsulosin HCl - 0.4mg, Dutasteride - 0.5mg	Capsule, hard	2,168,962 L.L
G04CA52	DUTASTERIDE/TAMSULOSINE ARROW	G	Tamsulosin HCl - 0.4mg, Dutasteride - 0.5mg	Capsule	1,337,123 L.L
J07CA11	DIPHTHERIA, TETANUS,PERTUSSIS, HEPATITIS B AND HAEMOPHILUS INFLUENZAE TYPE B CONJUGATE VACCINE	B	Diphteria Toxoid1 - ?25Lf (?30IU)/0.5ml, Tetanus toxoid1 - ?2.5Lf (?40IU)/0.5ml, Bordetella pertussis (Whole cell) - ?16OU (?4.0IU)/0.5ml, HBs Antigen (r DNA)1 - ?10mcg/0.5ml, H. Influenza type b, purified capsular polysaccharide2 - 10mcg/0.5ml, 1 adsorbed on aluminium phosphate, Al+++ - ?1.25mg , 2 conjugated to tetanos toxoid carrier protein -	Injectable suspension	1,515,854 L.L
N02AA59	DOLOSPASMINE COMP	B	Codeine phosphate - 40 mg, Hexahydro-adipenine HCl - 50 mg, Propyphenazone - 500 mg	Suppository	267,489 L.L

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