Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS TYPE SG	G	Potassium chloride - 3.92g/l, Magnesium chloride, 6H2O - 5.32g/l, Calcium chloride, 2H2O - 8.99g/l, Sodium acetate, 3H2O - 166.7g/l, Sodium chloride - 214.76g/l		Injectable solution	L.L
R05X	COLDIN	G	Caffeine - 30mg, Noscapine - 10mg, Pseudoephedrine HCl - 30mg, Pyrilamine maleate (Mepyramine) - 15mg, Paracetamol - 300mg		Capsule	386,515 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS L	G	Potassium chloride - K+:1.5 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.75 mmol/l, Sodium acetate - Cl-:106.5 mmol/l, Sodium chloride - Na+:135 mmol/l		Injectable solution	L.L
R05X	COLD-MED	G	Caffeine - 30mg, Noscapine - 10mg, Pseudoephedrine HCl - 30mg, Pyrilamine Maleate (Mepyramine) - 15mg, Paracetamol - 300mg		Capsule	386,515 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LM	G	Potassium chloride - K+:2.00 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.75 mmol/l, Sodium acetate - Cl-:112 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C09DB07	CANDAM	G	Candesartan cilexetil - 8mg, Amlodipine - 5mg		Capsule, hard	1,376,095 L.L
R05X	COLDIN	G	Glyceryl guaiacolate - 15mg/5ml, Pseudoephedrine HCl - 15mg/5ml, Pyrilamine maleate - 6.25mg/5ml, Paracetamol - 120mg/5ml		Syrup	386,515 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS	G	Potassium chloride - K+:1.5 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.75 mmol/l, Sodium acetate - Cl-:111.5 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C09DB07	CORONOPINE	G	Candesartan cilexetil - 8mg, Amlodipine - 5mg		Capsule, hard	1,368,032 L.L
R05X	COLD-MED	G	Glyceryl guaiacolate - 15mg/5ml, Pseudoephedrine HCl - 15mg/5ml, Pyrilamine maleate - 6.25mg/5ml, Paracetamol - 120mg/5ml		Syrup	386,515 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS2	G	Potassium chloride - K+:1.5 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.5 mmol/l, Sodium acetate - Cl-:111 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C09DB07	CANDAM	G	Candesartan cilexetil - 16mg, Amlodipine - 5mg		Capsule, hard	1,376,095 L.L
M01AB05	CLOREN ADULTS	G	Diclofenac sodium - 100mg	100mg	Suppository	598,970 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS3	G	Potassium chloride - K+:2.00 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.60 mmol/l, Sodium acetate - Cl-:112 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C09DB07	CORONOPINE	G	Candesartan cilexetil - 16mg, Amlodipine - 5mg		Capsule, hard	1,638,144 L.L
P01BA02	CORVAQUINE	G	Hydroxychloroquine sulfate - 200mg	200mg	Tablet, film coated	1,087,873 L.L
R05X	CODOPALM EXPECTORANT	G	Ipeca Tincture - 3mg, Promethazine HCl - 100mg, Potassium guaiacosulfonate - 0.9g		Syrup	153,582 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS R	G	Potassium chloride - K+:1.00 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.40 mmol/l, Sodium acetate - Cl-:105.8 mmol/l, Sodium chloride - Na+:140.5 mmol/l		Injectable solution	L.L
C09DB07	CANDAM	G	Candesartan cilexetil - 16mg, Amlodipine - 10mg		Capsule, hard	1,376,095 L.L
R05X	CODOPALM EXPECTORANT	G	Ipeca Tincture - 3mg, Promethazine HCl - 100mg, Potassium guaiacosulfonate - 0.9g		Syrup	291,806 L.L
B05ZA	CONCENTRATE SOLUTIONFOR HEMODIALYSIS TYPE A	G	Hemodialytics, concentrates -		Injectable solution	L.L
C09DB07	CORONOPINE	G	Candesartan cilexetil - 16mg, Amlodipine - 10mg		Capsule, hard	1,540,044 L.L
M01AB05	CLOFEN	G	Diclofenac sodium - 75mg/3ml	75mg/3ml	Injectable solution	299,677 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS TYPE B+	G	Hemodialytics, concentrates -		Injectable solution	L.L
C09DB07	CORONOPINE	G	Candesartan cilexetil - 8mg, Amlodipine - 10mg		Capsule, hard	1,368,032 L.L
G03DA04	CYCLOGEST	G	Progesterone - 400mg	400mg	Pessary	1,546,763 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS TYPE J	G	Hemodialytics, concentrates -		Injectable solution	L.L
J01DH51	CELLABAXIN	G	Imipenem (monohydrate) - 500mg, Cilastatin (sodium) - 500mg		Injectable solution	10,699,559 L.L
J01DH51	CILANEM	G	Imipenem anhydrous - 500mg, Cilastatin (sodium) - 500mg		Injectable solution	850,652 L.L
R05X	COLDIN-H	G	Paracetamol - 300mg, Mepyramine maleate - 15mg, Noscapine - 10mg		Capsule	386,515 L.L