Rubella

Rubella and Congenital Rubella Syndrome

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

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All

ATC	Name	B/G	Ingredients	Dosage	Form	Price
C03DA01	ALDACTONE	B	Spironolactone - 100mg	100mg	Tablet	458,250 L.L
C03DA01	ALDACTONE	B	Spironolactone - 25mg	25mg	Tablet	237,860 L.L
C03CA01	APO-FUROSEMIDE	G	Furosemide - 40mg	40mg	Tablet, scored	862,747 L.L
C03BA11	ADEX	G	Indapamide - 1.5mg	1.5mg	Tablet, prolonged release	296,989 L.L
C02LA51	ADELPHAN ESIDREX	B	Reserpine - 0.1mg, Hydrochlorothiazide - 10mg, Dihydralazine - 10mg		Tablet	371,157 L.L
C02AB02	ALDOMET	B	Methyldopa - 250mg	250mg	Tablet, coated	644,400 L.L
C02AB02	ALDOMET	B	Methyldopa - 500mg	500mg	Tablet, coated	856,708 L.L
C01CA24	ADRENALINE 1 MG I.V.	G	Adrenaline - 1mg/ml	1mg/ml	Injectable solution	2,239,738 L.L
C01CA24	ADRENALINE RENAUDIN	G	Epinephrine (tartrate) - 1mg/ml	1mg	Injectable solution	444,812 L.L
C01CA24	ADRENALINE SALF	G	Adrenaline - 1mg/ml	1mg/ml	Injectable solution	220,390 L.L
C01CA24	ADRENALINE AGUETTANT	G	Adrenaline - 0.1mg/ml	0.1mg/ml	Injectable solution	13,990,891 L.L
C01BD01	AMIODARONE BIOGARAN	G	Amiodarone (HCl) - 200mg	200mg	Tablet	345,368 L.L
B05XA31	ADDAVEN	G	Chromic chloride 6H2O - 53mcg/10ml, Copper chloride dihydrate - 1.02mg/10ml, Ferric Chloride hexahydrate - 5.40mg/10ml, Manganese chloride 4H2O - 198mcg/10ml, Potassium iodide - 166mcg/10ml, Sodium fluoride - 2.10mg/10ml		Injectable concentrate for solution	4,065,124 L.L
B05CX01	ALDEX	G	Dextrose, H2O - 5g/100ml	5g/100ml	Injectable solution	174,062 L.L
B05CX01	ALDEX	G	Dextrose, H2O - 5g/100ml	5g/100ml	Injectable solution	174,062 L.L
B05CX01	ALDEX	G	Dextrose, H2O - 5g/100ml	5g/100ml	Injectable solution	170,630 L.L
B05CX01	ALDEX	G	Dextrose, H2O - 5g/100ml	5g/100ml	Injectable solution	182,720 L.L
B05CX01	ALDEX	G	Dextrose, H2O - 5g/100ml	5g/100ml	Injectable solution	205,933 L.L
B05BA01	AMINOVEN 10%	B	Glacial Acetic Acid 99% - 5.297g/l, L-Proline - 15.0g/l, L-Alanine - 15.0g/l, Glycine - 14.0g/l, L-Histidine - 3.00g/l, L-Arginine - 12.0g/l, L-Valine - 6.20g/l, L-Tryptophan - 2.00g/l, L-Threonine - 4.40g/l, L-Phenylalanine - 5.10g/l, L-Methionine - 4.30g/l, L-Lysine (monoacetate) - 6.60g/l, L-Leucine - 7.40g/l, L-Isoleucine - 5.00g/l		Injectable solution	951,440 L.L
B05BA01	AMINOVEN INFANT	B	L-Leucine - 13g/l, L-Isoleucine - 8g/l, L-Lysine Acetate - 12g/l, L-Methionine - 3.12g/l, L-Phenylalanine - 3.75g/l, L-Threonine - 4.40g/l, L-Tryptophan - 2.01g/l, L-Valine - 9g/l, Arginine - 7.5g/l, L-Histidine - 4.76g/l, Glycine - 4.15g/l, L-Taurine - 0.40g/l, L-Serine - 7.67g/l, L-Alanine - 9.3g/l, L-Proline - 9.71g/l, N-Acetyl-L-Tyrosine - 5.176g/l, N-Acetyl-L-Cysteine - 0.70g/l, L-Malic Acid - 2.62g/l	10%	Injectable solution	880,217 L.L
B05BA01	AMINOPLASMAL B. BRAUN	B	Amino acids - 10%	10%	Injectable solution	1,036,103 L.L
B05AA01	ALBUKEY	BioHuman	Albumin human - 20%	20%	Injectable solution	4,863,366 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	3,240,004 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	6,353,687 L.L
B05AA01	ALBUTEIN	BioHuman	Albumin human - 20%	20%	Injectable solution	7,154,928 L.L
B05AA01	ALBUTEIN	BioHuman	Albumin human - 20%		Injectable solution	4,031,528 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 10,000IU	10000IU	Injectable solution	4,036,903 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 10,000IU	10,000IU	Injectable solution	10,661,285 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 4000IU	4000IU	Injectable solution	8,728,144 L.L

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