Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
D10AD03	DIFFERIN	B	Adapalene - 0.1g/100g	0.1%	Gel	503,941 L.L
D10AD03	DIFADERM	G	Adapalene - 0.3%	0.3%	Gel	952,208 L.L
D10AD04	ROACCUTANE	B	Isotretinoin - 0.05%	0.05%	Gel	932,627 L.L
D10AD51	ERYLIK	G	Tretinoin - 0.025%, Erythromycin - 4%		Gel	378,964 L.L
D10AD51	RETINOMYCIN	G	Tretinoin - 0.025%, Erythromycin - 4%		Gel	662,962 L.L
D10AD51	CLINIDERM T	G	Tretinoin - 0.025%, Clindamycin (phosphate) - 1%		Gel	801,186 L.L
C05AE03	DILTIGEL	G	Diltiazem HCl - 2%	2%	Gel	632,950 L.L
D10AD51	MEDCLINIDERM-T	G	Tretinoin - 0.025%, Clindamycin (phosphate) - 1%		Gel	801,186 L.L
D10AD51	CLINIDERM T	G	Tretinoin - 0.05%, Clindamycin (phosphate) - 1%		Gel	890,776 L.L
D10AD51	MEDCLINIDERM-T	G	Tretinoin - 0.05%, Clindamycin (phosphate) - 1%		Gel	890,776 L.L
D10AD53	EPIDUO	B	Adapalene - 0.1%, Benzoyl peroxide - 2.5%		Gel	2,088,331 L.L
C05BA53	CONTRACTUBEX	B	Allantoin - 1g/100g, Cepae - 10g/100g, Heparin - 5000IU/100g		Gel	498,566 L.L
D10AD53	EPIDUO FORTE	B	Adapalene - 0.3%, Benzoyl peroxide - 2.5%		Gel	2,201,214 L.L
C05BA53	CONTRACTUBEX	B	Allantoin - 1g/100g, Cepae - 10g/100g, Heparin - 5,000IU/100g		Gel	1,183,925 L.L
D10AE01	BENZAC AC	G	Benzoyl peroxide - 10g/100g	10%	Gel	416,591 L.L
D10AE01	BENZAC AC	G	Benzoyl peroxide - 5g/100g	5%	Gel	388,370 L.L
D10AF01	CLINIDERM	G	Clindamycin (phosphate) - 1%	1%	Gel	712,876 L.L
S01AD09	VIRGAN	B	Ganciclovir - 1.5mg/g	1.5mg/g	Gel	804,962 L.L
S01AD09	GANVIR	G	Ganciclovir - 0.15%	0.15%	Gel	698,798 L.L
D10AF02	SPOTEX	G	Erythromycin - 4%	4%	Gel	854,684 L.L
D10AF05	NAXIDERM	G	Nadifloxacin - 1%	1%	Gel	826,783 L.L
S01AE01	FLOXEDOL	G	Ofloxacin - 3mg/ml	3mg/ml	Gel	339,992 L.L
D10AF51	DUAC ONCE DAILY	B	Clindamycin (phosphate) - 1%, Benzoyl peroxide - 5%		Gel	1,658,302 L.L
C05CA05	VENOSMIL	G	Hidrosmin - 2%	2%	Gel	588,603 L.L
M02AA07	PIROXICALM	G	Piroxicam - 0.5%	0.5%	Gel	207,336 L.L
M02AA10	FASTUM	B	Ketoprofen - 2.5g/100g	2.5%	Gel	177,387 L.L
M02AA10	FASTUM	B	Ketoprofen - 2.5g/100g	2.5%	Gel	337,304 L.L
M02AA10	ACHONID GEL	G	Ketoprofen - 2.5%	2.5%	Gel	179,179 L.L
M02AA15	DICLOGESIC	G	Diclofenac sodium (diethylamine) - 10mg/g	1%	Gel	135,728 L.L
M02AA15	LOCAGEL	G	Diclofenac sodium (diethylamine) - 10mg/g	10mg/g	Gel	223,078 L.L