Rubella

Rubella and Congenital Rubella Syndrome

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

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All

ATC	Name	B/G	Ingredients	Dosage	Form	Price
S01LA05	EYLEA	BioTech	Aflibercept - 40mg/ml	40mg/ml	Injectable solution	65,161,855 L.L
S01LA05	EYLEA	BioTech	Aflibercept - 40mg/ml	40mg/ml	Injectable solution	L.L
S01LA05	EYLEA	BioTech	Aflibercept - 8mg/0.07ml	114.3mg/ml	Injectable solution	78,332,038 L.L
A16AB04	FABRAZYME	BioTech	Agalsidase beta - 35mg	35mg	Injectable powder for concentrate for solution	L.L
A16AB04	FABRAZYME	BioTech	Agalsidase beta - 35mg	35mg	Injectable powder for concentrate for solution	295,038,213 L.L
P02CA03	ALBENDA	G	Albendazole - 100mg/5ml	400mg/20ml	Suspension	129,009 L.L
P02CA03	ALBENDA	G	Albendazole - 200mg	200mg	Tablet	116,914 L.L
P02CA03	ALBENDAZOLE-UBSA	G	Albendazole - 200mg	200mg	Tablet	127,985 L.L
P02CA03	ANDAZOL	G	Albendazole - 200mg	200mg	Tablet, film coated	302,365 L.L
P02CA03	ZENTEL	B	Albendazole - 400mg	400mg	Tablet	169,324 L.L
B05AA01	YDRALBUM 200G/L	BioHuman	Albumin human - 10g/50ml		Injectable solution	3,417,391 L.L
B05AA01	ALBUKEY	BioHuman	Albumin human - 20%	20%	Injectable solution	4,863,366 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	3,240,004 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	6,353,687 L.L
B05AA01	ALBUTEIN	BioHuman	Albumin human - 20%	20%	Injectable solution	7,154,928 L.L
B05AA01	ALBUTEIN	BioHuman	Albumin human - 20%		Injectable solution	4,031,528 L.L
B05AA01	HUMAN ALBUMIN "OCTAPHARMA" 20%	BioHuman	Albumin human - 20%	20%	Injectable solution	4,863,366 L.L
B05AA01	HUMAN ALBUMIN 20% SOLUTION	BioHuman	Albumin human - 20%	20%	Injectable solution	4,343,343 L.L
B05AA01	HUMAN ALBUMIN BEHRING 20%, LOW SALT	BioHuman	Albumin human - 20%	20%	Injectable solution	4,343,343 L.L
B05AA01	PLASBUMIN-20 ALBUMIN (HUMAN)	BioHuman	Albumin human - 20%	20%	Injectable solution	3,641,813 L.L
B05AA01	ALBUREL HUMAN ALBUMIN BP	BioHuman	Albumin human - 20%	20%	Injectable solution	L.L
B05AA01	VIALEBEX	BioHuman	Albumin human - 200g/L	200g/L	Injectable solution	3,417,391 L.L
B05AA01	UMAN ALBUMIN	BioHuman	Albumin human - 20g/100ml	10g/50ml	Injectable solution	3,598,810 L.L
L01ED03	ALECENSA	B	Alectinib - 150mg	150mg	Capsule, hard	490,837,809 L.L
L01ED03	ALECENSA	B	Alectinib - 150mg	150mg	Capsule, hard	L.L
M05BA04	APO-ALENDRONATE	G	Alendronate (monosodium trihydrate) - 70mg	70mg	Tablet	981,005 L.L
M05BA04	MARVIL 70	G	Alendronate (monosodium trihydrate) - 70mg	70mg	Tablet, coated	1,173,175 L.L
M05BA04	FOSAMAX 70MG ONCE WEEKLY	B	Alendronate - 70mg	70mg	Tablet	1,988,887 L.L
M05BA04	OREK	G	Alendronate - 70mg	70mg	Tablet, coated	2,404,838 L.L
M05BA04	STRONDEX 70	G	Alendronate sodium - 70mg	70mg	Tablet	1,305,447 L.L

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