Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
B05CX01	DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	158,587 L.L
M01AE17	DEXON	G	Dexketoprofen - 25mg	25mg	Tablet, film coated	239,204 L.L
B05CX01	DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
R06AX27	DELINE	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Syrup	197,097 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	193,062 L.L
R06AX27	DELINE-MED	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Syrup	259,810 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
R06AX27	DESLAMED	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	323,802 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	158,587 L.L
M01AE17	DEXIREN	G	Dexketoprofen - 50mg/2ml	50mg/2ml	Injectable solution	467,657 L.L
R06AX27	DESLOR CHAPHA	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	323,802 L.L
B05CX01	DEXTROSE INJECTION 5%	G	Dextrose, H2O - 5g/100ml		Injectable solution	212,797 L.L
R06AX27	DESLORATADINE ARROW	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	249,955 L.L
R06AX27	DESLORATADINE ARROW	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	256,674 L.L
L01EL01	DULLARMA	G	Ibrutinib - 140mg	140mg	Capsule, hard	422,860,803 L.L
G04BE08	DURALIS	G	Tadalafil - 10mg	10mg	Tablet, film coated	1,187,701 L.L
N02BE01	DOLOPAN	G	Paracetamol - 500mg	500mg	Tablet, film coated	135,664 L.L
D10AD03	DIFADERM	G	Adapalene - 0.1%	0.1%	Gel	414,671 L.L
N02BE01	DOLOPAN	G	Paracetamol - 500mg	500mg	Tablet, film coated	317,403 L.L
N02BE01	DOLOPAN	G	Paracetamol - 500mg	500mg	Tablet, film coated	380,115 L.L
D10AD03	DIFADERM	G	Adapalene - 0.3%	0.3%	Gel	952,208 L.L
N02BE01	DOLOPAN	G	Paracetamol - 500mg	500mg	Tablet, film coated	317,403 L.L
N06AX16	DEFAXINE	G	Venlafaxine (HCl) - 75mg	75mg	Capsule, extended release	724,395 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	148,566 L.L
N04BC07	DACEPTON	G	Apomorphine HCl - 30mg/3ml	30mg/3ml	Injectable solution	13,404,432 L.L
N06AX16	DEPREVIX HELLAS	G	Venlafaxine - 75mg	75mg	Capsule, prolonged release	564,414 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	179,456 L.L
C05AE03	DILTIGEL	G	Diltiazem HCl - 2%	2%	Gel	632,950 L.L
N04BC07	DACEPTON	G	Apomorphine HCl Hemihydrate - 100mg/20ml	100mg/20ml	Injectable solution	12,678,532 L.L
N06AX16	DEPREVIX HELLAS	G	Venlafaxine - 75mg	75mg	Capsule, prolonged release	564,414 L.L