Rubella

Rubella and Congenital Rubella Syndrome

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

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All

ATC	Name	B/G	Ingredients	Dosage	Form	Price
D01AE15	TERAFAN	G	Terbinafine HCl - 1%	1%	Solution	355,798 L.L
S01AA09	TETRACYCLINE EYE OINTMENT	G	Tetracycline HCl - 1%	1%	Ointment	71,672 L.L
S01AA12	TOBRACIN	G	Tobramycin - 0.3%	0.3%	Drops	322,522 L.L
S01AA12	TOBRASTILL	G	Tobramycin - 0.3%	0.3%	Drops solution	258,018 L.L
S01AA12	TOBRIN	G	Tobramycin - 0.3%	0.3%	Drops	169,324 L.L
D01BA02	TERAFAN	G	Terbinafine HCl - 250mg	250mg	Tablet, scored	725,675 L.L
S01AA12	TOBRACIN	G	Tobramycin - 0.3%	0.3%	Ointment	280,863 L.L
D01BA02	TERMINUS	G	Terbinafine HCl - 250mg	250mg	Tablet	483,783 L.L
D02	TRIO-CID	G	Salicylic acid - 24%	24%	Film forming solution	870,298 L.L
C09DB04	TWINCARD 80/10	G	Telmisartan - 80mg, Amlodipine - 10mg		Tablet	1,460,309 L.L
C09DB04	TWINCARD 80/5	G	Telmisartan - 80mg, Amlodipine - 5mg		Tablet	1,131,387 L.L
S01AE06	TYMER	G	Gatifloxacin (sesquihydrate) - 3mg/ml	3mg/ml	Drops solution	427,342 L.L
H02AB08	TRIACORT	G	Triamcinolone acetonide - 40mg/ml	40mg/ml	Injectable suspension	745,833 L.L
C08CA01	TORANS	G	Amlodipine (besylate) - 5mg	5mg	Tablet	518,339 L.L
J02AC02	TRACON	G	Itraconazole - 100mg	100mg	Capsule	559,038 L.L
C08CA01	TORANS	G	Amlodipine (besylate) - 10mg	10mg	Tablet	716,716 L.L
A04AA01	TRONDAMET	G	Ondansetron (HCl) - 4mg/2ml	4mg/2ml	Injectable solution	2,027,858 L.L
R03BB04	TIOVA-T	G	Tiotropium bromide monohydrate - 18mcg	18mcg	Rotacaps	384,339 L.L
L04AD02	TACROGRAF 1	G	Tacrolimus - 1mg	1mg	Capsule	12,679,940 L.L
N06BX06	TRAUSAN	G	Citicoline - 100mg/ml	100mg/ml	Drops solution	807,649 L.L
D06AA04	TETRACYCLINE OINTMENT	G	Tetracycline HCl - 3%	3%	Ointment	107,507 L.L
A04AA01	TRONDAMET	G	Ondansetron (HCl) - 8mg/4ml	2mg/ml	Injectable solution	2,027,858 L.L
L04AD02	TACROGRAF 5	G	Tacrolimus - 5mg	5mg	Capsule	67,507,154 L.L
R03DA04	THEOSOL ELIXIR	G	Théophylline - 25mg/5ml	25mg/5ml	Elixir	312,283 L.L
R03DA04	THEODEX	G	Theophylline - 80mg/15ml	80mg/15ml	Elixir	156,142 L.L
B01AC04	THROMBO	G	Clopidogrel - 75mg	75mg	Tablet, film coated	764,646 L.L
L04AD02	TACROGRAF 0.5	G	Tacrolimus - 0.5mg	0.5mg	Capsule	7,004,024 L.L
B01AC04	TROKEN	G	Clopidogrel (Bisulfate) - 75mg	75mg	Tablet, film coated	1,148,985 L.L
M03BB52	TRANCODEX	G	Paracetamol - 450mg, Chlormezanone - 100mg		Tablet	99,828 L.L
R03DB05	THEODEX	G	Ipeca fluide extract - 20mg, Aminophylline - 150mg, Caffeine - 100mg, Ephedrine - 15mg		Tablet	156,142 L.L

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