Rubella

Rubella and Congenital Rubella Syndrome

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

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All

ATC	Name	B/G	Ingredients	Dosage	Form	Price
J01RA	SPIRAGYL FORTE	G	Metronidazole - 250mg, Spiramycin - 1,500,000IU		Tablet, scored	474,824 L.L
N06AB06	SERTRALINE BIOGARAN	G	Sertraline HCl - 50mg	50mg	Capsule	520,067 L.L
B05XA03	SERUFLEX SODIUM CHLORIDE 0.9% INJECTION, USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	156,288 L.L
N06AB06	SOLOTIK	G	Sertraline HCl - 50mg	50mg	Tablet, film coated	428,686 L.L
A03AA04	SPASMINE (Mebeverine HCl 200mg SR)	G	Mebeverine HCl - 200mg	200mg	Capsule, slow release	712,876 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	4,143,943 L.L
L04AA27	SCLEMOD	G	Fingolimod Hydrochloride - 0.5mg	0.5mg	Capsule	18,264,981 L.L
M01AE03	SOLKET	G	Ketoprofen Lysine salt - 80mg	80mg	Powder for solution	636,981 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	3,985,356 L.L
L04AA27	SCLEMOD	G	Fingolimod Hydrochloride - 0.5mg	0.5mg	Capsule	17,079,643 L.L
M01AE03	SOLKET INFLAMMATION AND PAIN	G	Ketoprofen Lysine salt - 0.16%	0.16%	Spray	946,065 L.L
N06AB06	SERTRA TAD	G	Sertraline HCl - 100mg	100mg	Tablet, film coated	1,124,796 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	5,566,628 L.L
N06AB06	SOLOTIK	G	Sertraline HCl - 100mg	100mg	Tablet, film coated	616,824 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	519,736 L.L
N06AB06	SERTRALINE BIOGARAN	G	Sertraline HCl - 25mg	25mg	Capsule	130,353 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	167,780 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	167,780 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	166,708 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	174,553 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	188,772 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	209,151 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	222,941 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	349,596 L.L
A03AX13	SIMETHICONE	G	Dimethicone - 2g/100ml	2g/100ml	Emulsion	212,327 L.L
A10BA02	SIOFOR	G	Metformin HCl - 850mg	850mg	Tablet, film coated	174,700 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	182,720 L.L
B05	SOLUFLEX POTASSIUM CHLORIDE 40meq/l SODIUM CHLORIDE 0.9% INJECTION USP	G	Sodium chloride - 0.9%, Potassium chloride - 40meq/l		Injectable solution	293,041 L.L
B05XA03	SODIUM CHLORIDE	G	Sodium chloride - 0.9%	0.9%	Injectable solution	182,720 L.L
B05	SOLUFLEX POTASSIUM CHLORIDE 20meq/l SODIUM CHLORIDE 0.9% INJECTION USP	G	Sodium chloride - 0.9%, Potassium chloride - 20meq/l		Injectable solution	232,134 L.L

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