Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
A03BA01	ATROPINE	G	Atropine sulfate - 1mg/ml	1mg/ml	Injectable solution	702,149 L.L
B05AA01	HUMAN ALBUMIN "OCTAPHARMA" 20%	BioHuman	Albumin human - 20%	20%	Injectable solution	4,863,366 L.L
B05XA03	SODIUM CHLORIDE INJECTION/ DEMO	G	Sodium chloride - 0.9% w/v	0.9% w/v	Injectable solution	1,419,098 L.L
A03BA01	ATROPINE SULFATE RENAUDIN	G	Atropine sulfate - 1mg/ml	0.1%	Injectable solution	397,777 L.L
B05AA01	HUMAN ALBUMIN 20% SOLUTION	BioHuman	Albumin human - 20%	20%	Injectable solution	4,177,896 L.L
B05XA03	SODIUM CHLORIDE INJECTION/ DEMO	G	Sodium chloride - 0.9% w/v	0.9% w/v	Injectable solution	567,102 L.L
H02AB02	DEXAMETHASON-PANPHARMA	G	Dexamethasone - 5mg/1ml	5mg/1ml	Injectable solution	368,213 L.L
A03BA01	ATROPINE I.V. 0.25 MG.	G	Atropine - 0.25mg/ml	0.25mg/ml	Injectable solution	2,412,129 L.L
B05AA01	HUMAN ALBUMIN BEHRING 20%, LOW SALT	BioHuman	Albumin human - 20%	20%	Injectable solution	4,177,896 L.L
B05XA03	SOLUFLEX SODIUM CHLORIDE 0.9% INJECTION USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	180,421 L.L
H02AB02	DEXAMETHASONE MEDIS	G	Dexamethasone Phosphate - 4mg/1ml	4mg/1ml	Injectable solution	1,154,361 L.L
N02BG06	ACUPAN	B	Nefopam HCl - 20mg	20mg	Injectable solution	365,525 L.L
A03BA01	ATROPINE	G	Atropine sulfate - 0.5mg/ml	0.5mg/ml	Injectable solution	680,315 L.L
B05AA01	PLASBUMIN-20 ALBUMIN (HUMAN)	BioHuman	Albumin human - 20%	20%	Injectable solution	3,641,813 L.L
B05XA03	SOLUFLEX SODIUM CHLORIDE 0.9% INJECTION USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	180,421 L.L
L01FG01	ZIRABEV	BioTech	Bevacizumab - 100mg/4ml	100mg/4ml	Injectable solution	14,800,115 L.L
N02BG06	NEO-PAN	G	Nefopam HCl - 20mg/ml	20mg/ml	Injectable solution	494,534 L.L
A03BA01	ATROPINE SULFATE RENAUDIN	G	Atropine sulfate - 0.5mg/ml	0.5mg	Injectable solution	385,683 L.L
B05AA01	UMAN ALBUMIN	BioHuman	Albumin human - 20g/100ml	10g/50ml	Injectable solution	3,598,810 L.L
B05XA03	SOLUFLEX SODIUM CHLORIDE 0.9% INJECTION, USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	218,344 L.L
L01FG02	CYRAMZA	BioTech	Ramucirumab - 100mg/10ml	100mg/10ml	Injectable solution	47,779,251 L.L
A03BA01	ATROPINE SULFATEAGUETTANT	G	Atropine - 0.1mg/ml	0.1mg/ml	Injectable solution	7,805,376 L.L
B05AA01	VIALEBEX	BioHuman	Albumin human - 200g/L	200g/L	Injectable solution	3,417,391 L.L
B05XA03	SOLUFLEX SODIUM CHLORIDE 0.9% INJECTION, USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	203,405 L.L
L01FG02	CYRAMZA	BioTech	Ramucirumab - 500mg/50ml	500mg/50ml	Injectable solution	218,656,548 L.L
B05AA01	YDRALBUM 200G/L	BioHuman	Albumin human - 10g/50ml		Injectable solution	3,417,391 L.L
B05XA03	SOLUFLEX SODIUM CHLORIDE 0.9% INJECTION, USP	G	Sodium chloride - 0.9%	0.9%	Injectable solution	179,272 L.L
A12CX	PHOSPHATE DIPOTASSIQUE RENAUDIN	G	Phosphate dipotassique - 174.20mg/ml	174.20mg/ml	Injectable solution	1,189,301 L.L
B05AA06	GELASPAN	B	Gelatine, succinylated - 4%	4%	Injectable solution	9,107,572 L.L
B05XA03	0.45% SODIUM CHLORIDE INJECTION USP	G	Sodium chloride - 0.45%	0.45%	Injectable solution	160,885 L.L