Meningococcal Infection

Generalities
Agent	Bacteria: Neisseria meningitidis (meningococcus), Gram negative diplococci - 12 serogroups have been identified - Six serogrouprs are responsible of invasive infection: A, B, C, W135, X, and Y.
Incubation period	2-10 days, commonly 3-4 days
Period of transmissibility	Cases should be considered infectious from exposure until 24 hours after starting treatment of prophylaxis with appropriate antibiotics with substantial concentrations in oro/nasopharyngeal secretions
Reservoir	- Humans - Asymptomatic carriage in nasopharynx is common.
Modes of transmission	- Person-to-person transmission by direct contact with respiratory droplets of infected people - Most cases acquired through exposure to asymptomatic carriers
Clinical presentation	- Bacterial meningitis - Septicaemia: rare ans severe with purpura - Complications: cerebral lesions, hearing loss, learning disorders among 10-20% of survivors - Case fatality: 8-15% despite treatment
Resources
Case definition	- MOPH circular no. 63 (2007) - MOPH circular no. 72 (2003): contacts
Forms	- Meningitis reporting form - Meningitis investigation form
Data	- Weekly report

ATC	Name	B/G	Ingredients	Dosage	Form	Price
M02AA15	DICLOGESIC	G	Diclofenac sodium (diethylamine) - 10mg/g	1%	Gel	135,728 L.L
N01AX10	DORMIFOR	G	Propofol - 1%	1%	Injectable emulsion	1,081,473 L.L
R06AX27	DELINE	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Syrup	197,097 L.L
R06AX27	DELINE-MED	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Syrup	259,810 L.L
R06AX27	DESLAMED	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	323,802 L.L
R06AX27	DESLOR CHAPHA	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	323,802 L.L
R06AX27	DESLORATADINE ARROW	G	Desloratadine - 0.5mg/ml	0.5mg/ml	Solution	256,674 L.L
H02AB02	DECADRON	B	Dexamethasone - 0.5mg/5ml	0.5mg/5ml	Elixir	449,227 L.L
H02AB02	DEXAMETHASONE	G	Dexamethasone - 0.5mg/5ml	0.5mg/5ml	Elixir	119,026 L.L
G04CB02	DUTASTERIDE ARROW LAB	G	Dutasteride - 0.5mg	0.5mg	Capsule	1,166,455 L.L
G04CB02	DUTASTERIDE BIOGARAN	G	Dutasteride - 0.5mg	0.5mg	Capsule, soft	1,112,702 L.L
H02AB02	DECADRON	B	Dexamethasone - 0.5mg	0.5mg	Tablet, scored	378,240 L.L
G02CB03	DOSTINEX	B	Cabergoline - 0.5mg	0.5mg	Tablet, scored	415,247 L.L
G02CB03	DOSTINEX	B	Cabergoline - 0.5mg	0.5mg	Tablet, scored	1,628,737 L.L
D10AD03	DIFADERM	G	Adapalene - 0.3%	0.3%	Gel	952,208 L.L
L02AE04	DECAPEPTYL	B	Triptorelin - 0.1mg	0.1mg	Injectable lyophilised powder for solution+diluent	2,366,507 L.L
R01AA07	DECOZAL	G	Xylometazoline HCl - 0.1%	0.1%	Metered dose spray	147,823 L.L
R01AA07	DECOZAL	G	Xylometazoline HCl - 0.1%	0.1%	Drops	145,135 L.L
D10AD03	DIFFERIN	B	Adapalene - 0.1g/100g	0.1%	Cream	521,411 L.L
D10AD03	DIFADERM	G	Adapalene - 0.1%	0.1%	Gel	414,671 L.L
D10AD03	DIFFERIN	B	Adapalene - 0.1g/100g	0.1%	Gel	503,941 L.L
S01BC03	DICLOFTIL	G	Diclofenac sodium - 0.1%	0.1%	Drops solution	1,038,790 L.L
D07AD01	DERMOVATE	B	Clobetasol (propionate) - 0.5mg/g	0.05% w/w	Cream	290,270 L.L
D07AD01	DERMOVATE	B	Clobetasol (propionate) - 0.5mg/g	0.05% w/w	Ointment	290,270 L.L
D07AC01	DIPROSONE	B	Betamethasone (dipropionate) - 0.5mg/g	0.05%	Cream	291,614 L.L
R01AA07	DECOZAL	G	Xylometazoline HCl - 0.05%	0.05%	Metered dose spray	155,886 L.L
R01AA07	DECOZAL	G	Xylometazoline HCl - 0.05%	0.05%	Metered dose spray	108,851 L.L
D07AD01	DECLOBAN	G	Clobetasol (propionate) - 0.05%	0.05%	Cream	302,045 L.L
D07AD01	DERMASONE	G	Clobetasol (propionate) - 0.05%	0.05%	Cream	119,026 L.L
D07AD01	DECLOBAN	G	Clobetasol (propionate) - 0.05%	0.05%	Ointment	302,045 L.L