Meningococcal Infection

Generalities
Agent	Bacteria: Neisseria meningitidis (meningococcus), Gram negative diplococci - 12 serogroups have been identified - Six serogrouprs are responsible of invasive infection: A, B, C, W135, X, and Y.
Incubation period	2-10 days, commonly 3-4 days
Period of transmissibility	Cases should be considered infectious from exposure until 24 hours after starting treatment of prophylaxis with appropriate antibiotics with substantial concentrations in oro/nasopharyngeal secretions
Reservoir	- Humans - Asymptomatic carriage in nasopharynx is common.
Modes of transmission	- Person-to-person transmission by direct contact with respiratory droplets of infected people - Most cases acquired through exposure to asymptomatic carriers
Clinical presentation	- Bacterial meningitis - Septicaemia: rare ans severe with purpura - Complications: cerebral lesions, hearing loss, learning disorders among 10-20% of survivors - Case fatality: 8-15% despite treatment
Resources
Case definition	- MOPH circular no. 63 (2007) - MOPH circular no. 72 (2003): contacts
Forms	- Meningitis reporting form - Meningitis investigation form
Data	- Weekly report

ATC	Name	B/G	Ingredients	Dosage	Form	Price
S01AA09	TETRACYCLINE EYE OINTMENT	G	Tetracycline HCl - 1%	1%	Ointment	71,672 L.L
S01AA12	TOBRACIN	G	Tobramycin - 0.3%	0.3%	Drops	322,522 L.L
J01MA12	TAVAQUIN 500MG	G	Levofloxacin - 500mg	500mg	Tablet, film coated	787,492 L.L
L04AA31	TERAGIO	G	Teriflunomide - 14mg	14mg	Tablet	49,451,224 L.L
S01AA12	TOBRASTILL	G	Tobramycin - 0.3%	0.3%	Drops solution	258,018 L.L
L04AA31	TERAGIO	G	Teriflunomide - 14mg	14mg	Tablet	23,076,914 L.L
S01AA12	TOBRIN	G	Tobramycin - 0.3%	0.3%	Drops	169,324 L.L
S01AA12	TOBRACIN	G	Tobramycin - 0.3%	0.3%	Ointment	280,863 L.L
J01MA12	TAVAQUIN	G	Levofloxacin (hemihydrate) - 750mg	750mg	Tablet, film coated	1,389,533 L.L
C09CA07	TELMICARD 40	G	Telmisartan - 40mg	40mg	Tablet	659,123 L.L
C09CA07	TOLURA	G	Telmisartan - 40mg	40mg	Tablet	532,162 L.L
L01AC01	TEPADINA	G	Thiotepa - 100mg	100mg	Injectable powder for concentrate for solution	98,197,306 L.L
B03AA07	TIMOFEROL	G	Iron bivalent (as dried ferrous sulfate) - 50mg (172.73mg), Ascorbic acid - 30mg		Capsule	652,931 L.L
L01AX03	TEGOZOL	G	Temozolomide - 250mg	250mg	Capsule	24,856,894 L.L
C09CA07	TELMICARD 80	G	Telmisartan - 80mg	80mg	Tablet	865,179 L.L
L01AX03	TEMOZOLOMIDE ACCORD	G	Temozolomide - 250mg	250mg	Capsule, hard	13,397,927 L.L
C09CA07	TOLURA	G	Telmisartan - 80mg	80mg	Tablet	698,798 L.L
L01AX03	TEMOZOLOMIDE GP PHARM	G	Temozolomide - 250mg	250mg	Capsule, hard	12,058,004 L.L
S01AE06	TYMER	G	Gatifloxacin (sesquihydrate) - 3mg/ml	3mg/ml	Drops solution	427,342 L.L
G04CA02	TALUSIN	G	Tamsulosin HCl - 0.4mg	0.4mg	Capsule, modified release	683,440 L.L
L01AX03	TEGOZOL	G	Temozolomide - 100mg	100mg	Capsule	5,012,533 L.L
G04CA02	TAMSU GENERICON RETARD	G	Tamsulosin - 0.4mg	0.4mg	Capsule, hard, modified release	615,480 L.L
L01AX03	TEMOZOLOMIDE ACCORD	G	Temozolomide - 100mg	100mg	Capsule, hard	5,590,385 L.L
L01AX03	TEMOZOLOMIDE GP PHARM	G	Temozolomide - 100mg	100mg	Capsule, hard	4,511,279 L.L
L01AX03	TEMOZOLOMIDE ACCORD	G	Temozolomide - 20mg	20mg	Capsule, hard	1,153,017 L.L
L01AX03	TEMOZOLOMIDE GP PHARM	G	Temozolomide - 20mg	20mg	Capsule, hard	920,532 L.L
L01AX03	TEGOZOL	G	Temozolomide - 20mg	100mg	Capsule	1,022,664 L.L
L01AX03	TEMOZOLOMIDE ACCORD	G	Temozolomide - 5mg	5mg	Capsule, hard	1,153,017 L.L
L01AX03	TEMOZOLOMIDE GP PHARM	G	Temozolomide - 5mg	5mg	Capsule, hard	1,153,017 L.L
D11AH01	TACRUS	G	Tacrolimus monohydrate - 0.1%	0.1%	Ointment	1,857,190 L.L