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Look Alike Sound Alike Medicines


Announcement: Public Consultation: Revision of National LASA List - Your Input Needed!

Date: February 21st, 2024

Background:

In 2023, the initiative to create a National LASA (Look-Alike Sound-Alike) list was set into motion. The primary goal of this project was to identify LASA pairs among authorized medications in the Lebanese market, focusing on those with similar names or sound. Specifically, the compiled list featured drugs that exhibited either visual resemblance in terms of how the name of the drug is written (look alike) or phonetic similarity (sound alike). The final comprehensive national LASA list, combining both categories, is attached below. The full details related to each drug may be checked at the price list posted at the MoPH webpage.

A thorough process involving collaboration with Marketing Authorization Holders led to the compilation of a one comprehensive LASA list, attached below. As a final step before publication, we are extending an invitation to our stakeholders for their input during the last revision phase.

National Look Alike/Sound Alike (LASA) List

Invitation to Stakeholders:

In line with our commitment to transparency, safety, and continual improvement, the Quality Assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH) invites all stakeholders to participate in the revision of the National LASA list. This invitation is extended to Marketing Authorization Holders, Healthcare Professionals (HCPs), including but not limited to pharmacists, physicians, and nurses, as well as any individual or entity involved in pharmacovigilance activities in Lebanon.

Your Participation Matters:

Your active involvement in the public consultation phase is crucial for refining this important list. We welcome your valuable input, comments, and questions to enhance the accuracy and effectiveness of the National LASA list.

How to Participate:

Kindly provide your comments or feedback, by the 22nd of April 2024, through sending an email to either lasa.moph@gmail.com or lasa@moph.gov.lb. When naming your email, adhere to the convention: “LASA List Comments - [Your Company Name],” for example, "LASA List comments-Mersaco." Your cooperation with this naming convention is greatly appreciated.

Remarks:

The Quality Assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH) expresses gratitude to all stakeholders for their cooperation and dedication to advancing pharmacovigilance in Lebanon. Your engagement in the public consultation is invaluable, and together, we will establish new benchmarks for pharmaceutical safety and efficacy.

Thank you for your commitment to ensuring the highest standards in healthcare and medication safety.
 
Look Alike Sound Alike Project List to be filled by the drug distributors
 
On behalf of the Quality assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH), we are contacting you with an official request to provide information regarding your products in the context of a project on “Look-Alike Sound-Alike Medications”.

Literature shows that Look-Alike Sound-Alike (LASA) pairs are viewed as the cause of medication errors. LASA health products refer to names of different medicinal products that have orthographic similarities (look-alike in the way they are written), and/or phonetics similarities (sound-alike in the way they are pronounced), which is the main focus and scope of the required requested list. These similarities may pose serious health risk by causing errors in prescribing, dispensing or administering a product. LASA errors can result in overdosing, under-dosing, or inappropriate dosing.

Keeping in mind that potential for error is further increased by similar packaging, tablet appearance, tablet strength, or route of administration; which are not within this project scope.

The project aims to identify LASA pairs among the medications authorized for use in the Lebanese market that may be similarly written and/or have similar sounding brand names. Accordingly, a comprehensive list of LASA commonly confused medication names will be published.
 
You are therefore kindly requested to fill the provided excel sheet “LASA List to be filled with your products”, in which you shall identify any drug in your portfolio that matches another drug available for use in Lebanon that is written or pronounced like it.

To this end, you are kindly invited to apply the following instructions:
The excel sheet (link below): it is a list of the products authorized for use in Lebanon with their relevant information. It is extracted from the latest Drugs Public Price List from the MoPH’s official website. (extracted on 7th March, 2023)
LASA  List  to be filled by Drug distributors
 
For each of your products:
  1. In the “Agent” column (Column C), apply the filter to choose your company name; this will display only your products in the “Brand name” column (Column D).
  2. In the “MoH Drug Name” columns (column J), indicate for each of your products the identified list of drugs that may be written similarly to yours. 
  3. In the “MoH Drug Name” columns (column K) indicate for each of your products the identified list of drugs that may be pronounced similarly to yours. 
  4. For steps 3 and 4, please write NA If not applicable
  5. Fill the “Comment” column (Column L) with any information present that you may find relevant.
  6. Please refer to rows number 4, 5, and 6 as examples. These were extracted from the Institute for Safe Medications Practices List.
  7. Send us the filled excel sheet at the following email addresses: lasa.moph@gmail.com or lasa@moph.gov.lb
  8. Ensure that your file is named as follow: (name of the distributor-lasalist2023),Example: Mersaco-lasalist2023
 
You are kindly expected to reply back within 2 months after receiving this email (by May 31st, 2023), the latest.
 
Thank you for your time and cooperation.


Reminder,

Reference to previous communication related to the submission of the LASA (Look-Alike Sound-Alike) list, we would like to kindly remind all drug distributers and local manufacturers to complete the list by May 31st, 2023.

As per the previously shared instruction, the list must be filled out with utmost accuracy. It should be completed in accordance with the identified company's own LASA list. We stress the importance of adhering to these instructions to ensure the safety and efficacy of medication use.

In case there are no LASA products, please verify this by an email to lasa.moph@gmail.com.

We appreciate your cooperation in this matter.

Quality Assurance of Pharmaceutical Products Department
Lebanese National Pharmacovigilance Program
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ATC Name B/G Ingredients Dosage Form Price
H02B PREDALONE PLUS G Prednisolone sodium phosphate - 10mg/5ml, Dexchlorpheniramine maleate - 2mg/5ml Syrup 890,776 L.L
C07BB07 PRESCOR 5 PLUS G Bisoprolol - 5mg, Hydrochlorothiazide - 12.5mg Tablet, film coated 678,321 L.L
C09DB01 POVAM G Amlodipine (besylate) - 10mg, Valsartan - 160mg Tablet, film coated 857,372 L.L
R06AA52 PULMONAL EXPECTORANT G Diphenhydramine HCl - 0.015g/5ml, Ammonium HCl - 0.1g/5ml Syrup 177,899 L.L
A03AX12 PHLOROGLUCINOL/TRIMETHYLPHLOROGLUCINOL ARROW G Phloroglucinol - 40mg/4ml, Trimethylphloroglucinol - 0.04mg/4ml Injectable solution 940,690 L.L
B05BA10 PERIOLIMEL N4E B Olive oil + Soja oil - 45.00g, Alanine - 5.50g, Arginine - 3.72g, Aspartic Acid - 1.10g, Glutamic Acid - 1.90g, Glycine - 2.63g, Histidine - 2.26g, Isoleucine - 1.90g, Leucine - 2.63g, Lysine - 2.99g, Methionine - 1.90g, Phenylalanine - 2.63g, Proline - 2.26g, Serine - 1.50g, Threonine - 1.90g, Tryptophan - 0.64g, Tyrosine - 0.10g, Valine - 2.43g, Sodium acetate, 3H2O - 1.73g, Sodium glycerophosphate, H2O - 2.87g, Potassium chloride - 1.79g, Magnesium chloride, 6H2O - 0.67g, Calcium chloride 2H2O - 0.44g, Glucose monohydrate - 123.75g Injectable emulsion 5,288,020 L.L
L01XY02 PHESGO BioTech Pertuzumab - 600mg, Trastuzumab - 600mg Injectable solution 326,054,156 L.L
L01XY02 PHESGO BioTech Pertuzumab - 1200mg, Trastuzumab - 600mg Injectable solution 591,417,874 L.L
G03FB01 PROGYLUTON B Norgestrel - 0.5mg (tablet 2), Estradiol valerate - 2mg (tablet 1, tablet 2) Tablet 193,513 L.L
J01EE01 PAEDIATRIC CO-TRIMOXAZOLE MIXTURE G Trimethoprim - 40mg/5ml, Sulfamethoxazole - 200mg/5ml Suspension 190,698 L.L
A03CA02 PRIMAX G Clidinium bromide - 2.5mg, Chlordiazepoxide - 5mg Tablet 222,694 L.L
A03DB04 PANADOL WOMAN B Paracetamol - 500mg, Hyoscine butylbromide - 10mg Tablet, coated 436,749 L.L
M01AB55 PANCLO B12 G Diclofenac sodium - 75mg, Betamethasone disodium phosphate - 2mg, Hydroxocobalamin sulphate - 10mg Injectable solution 1,158,392 L.L
N01BB54 PRILA G Prilocaine - 2.5% w/w, Lidocaine - 2.5% w/w Cream 1,057,604 L.L
L01BA04 PEMETREXED NEAPOLIS G Pemetrexed (disodium) - 500mg Injectable powder L.L
G03GA30 PERGOVERIS BioHuman Follitropin alfa - 150IU, Lutropin Alfa - 75IU Injectable powder for solution+diluent 6,523,011 L.L
N02AJ06 PARACO-DENK 1000/60 G Paracetamol - 1000mg, Codeine phosphate hemihydrate - 60mg Suppository 636,981 L.L
R03AK06 PROPIONATE DE FLUTICASONE/ SALMETEROL ARROW G Salmeterol - 50mcg/dose, Fluticasone propionate - 100mcg/dose Inhalation powder 1,593,797 L.L
J07AL01 PNEUMOVAX 23 B Polysaccharides from each of 23 capsular types of Streptococcus pneumoniae - 25mcgx23serotypes/0.5ml Injectable solution 2,378,601 L.L
J07AL02 PREVENAR 13 B Polysaccharide for serotypes 1, 3, 4, 5 , 6A, 7F, 9V,14, 18C, 19A, 19F, 23F (2.2mcg)Polysaccharide for serotypes 6B (4.4mcg)Conjugated to CRM197 carrier protein and adsorbed on aluminium phosphate (0.125mg aluminium) - Injectable suspension 6,352,343 L.L
R03AK06 PROPIONATE DE FLUTICASONE/ SALMETEROL ARROW G Salmeterol - 50mcg/dose, Fluticasone propionate - 250mcg/dose Inhalation powder 1,980,824 L.L
C09BA04 PRETERAX ARGININE B Perindopril arginine - 2.5mg, Indapamide - 0.625mg Tablet, film coated 452,875 L.L
J07AL02 PNEUMOSIL (10-VALENT) G Pneumococcal polysaccharide conjugate vaccine (adsorbed) - Injectable suspension 3,386,483 L.L
J07AL02 PREVENAR 20 B Pneumococcal polysaccharide for serotypes 1, 3, 4, 5 , 6A, 7F,8, 9V,10A, 11A, 12F, 14, 15B, 18C, 19A, 19F,22F, 23F, 33F (2.2mcg) Pneumococcal polysaccharide for serotypes 6B (4.4mcg)Conjugated to CRM197 carrier protein (approximately 51mcg) adsorbed on aluminium phosphate (0.125mg aluminium) - Injectable suspension 7,415,107 L.L
R03AK06 PROPIONATE DE FLUTICASONE/ SALMETEROL ARROW G Salmeterol - 50mcg/dose, Fluticasone propionate - 500mcg/dose Inhalation powder 2,605,711 L.L
C09BB04 PRESORYL PLUS G Perindopril arginine - 5mg, Amlodipine (besylate) - 5mg Tablet 557,695 L.L
C09BB04 PRESORYL PLUS G Perindopril arginine - 10mg, Amlodipine (besylate) - 5mg Tablet 770,022 L.L
M01AE51 PROFINAL XP G Ibuprofen - 400mg, Caffeine - 65mg Caplet, film coated 286,238 L.L
C09BB04 PRESORYL PLUS G Perindopril arginine - 10mg, Amlodipine (besylate) - 10mg Tablet 770,022 L.L
J01CR05 PIPERACILINA/TAZOBACTAM SALA G Piperacillin (sodium) - 4g, Tazobactam (sodium) - 0.5g Injectable powder for solution 913,813 L.L
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