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Look Alike Sound Alike Medicines


Announcement: Public Consultation: Revision of National LASA List - Your Input Needed!

Date: February 21st, 2024

Background:

In 2023, the initiative to create a National LASA (Look-Alike Sound-Alike) list was set into motion. The primary goal of this project was to identify LASA pairs among authorized medications in the Lebanese market, focusing on those with similar names or sound. Specifically, the compiled list featured drugs that exhibited either visual resemblance in terms of how the name of the drug is written (look alike) or phonetic similarity (sound alike). The final comprehensive national LASA list, combining both categories, is attached below. The full details related to each drug may be checked at the price list posted at the MoPH webpage.

A thorough process involving collaboration with Marketing Authorization Holders led to the compilation of a one comprehensive LASA list, attached below. As a final step before publication, we are extending an invitation to our stakeholders for their input during the last revision phase.

National Look Alike/Sound Alike (LASA) List

Invitation to Stakeholders:

In line with our commitment to transparency, safety, and continual improvement, the Quality Assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH) invites all stakeholders to participate in the revision of the National LASA list. This invitation is extended to Marketing Authorization Holders, Healthcare Professionals (HCPs), including but not limited to pharmacists, physicians, and nurses, as well as any individual or entity involved in pharmacovigilance activities in Lebanon.

Your Participation Matters:

Your active involvement in the public consultation phase is crucial for refining this important list. We welcome your valuable input, comments, and questions to enhance the accuracy and effectiveness of the National LASA list.

How to Participate:

Kindly provide your comments or feedback, by the 22nd of April 2024, through sending an email to either lasa.moph@gmail.com or lasa@moph.gov.lb. When naming your email, adhere to the convention: “LASA List Comments - [Your Company Name],” for example, "LASA List comments-Mersaco." Your cooperation with this naming convention is greatly appreciated.

Remarks:

The Quality Assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH) expresses gratitude to all stakeholders for their cooperation and dedication to advancing pharmacovigilance in Lebanon. Your engagement in the public consultation is invaluable, and together, we will establish new benchmarks for pharmaceutical safety and efficacy.

Thank you for your commitment to ensuring the highest standards in healthcare and medication safety.
 
Look Alike Sound Alike Project List to be filled by the drug distributors
 
On behalf of the Quality assurance of Pharmaceutical Products Program at the Ministry of Public Health (MoPH), we are contacting you with an official request to provide information regarding your products in the context of a project on “Look-Alike Sound-Alike Medications”.

Literature shows that Look-Alike Sound-Alike (LASA) pairs are viewed as the cause of medication errors. LASA health products refer to names of different medicinal products that have orthographic similarities (look-alike in the way they are written), and/or phonetics similarities (sound-alike in the way they are pronounced), which is the main focus and scope of the required requested list. These similarities may pose serious health risk by causing errors in prescribing, dispensing or administering a product. LASA errors can result in overdosing, under-dosing, or inappropriate dosing.

Keeping in mind that potential for error is further increased by similar packaging, tablet appearance, tablet strength, or route of administration; which are not within this project scope.

The project aims to identify LASA pairs among the medications authorized for use in the Lebanese market that may be similarly written and/or have similar sounding brand names. Accordingly, a comprehensive list of LASA commonly confused medication names will be published.
 
You are therefore kindly requested to fill the provided excel sheet “LASA List to be filled with your products”, in which you shall identify any drug in your portfolio that matches another drug available for use in Lebanon that is written or pronounced like it.

To this end, you are kindly invited to apply the following instructions:
The excel sheet (link below): it is a list of the products authorized for use in Lebanon with their relevant information. It is extracted from the latest Drugs Public Price List from the MoPH’s official website. (extracted on 7th March, 2023)
LASA  List  to be filled by Drug distributors
 
For each of your products:
  1. In the “Agent” column (Column C), apply the filter to choose your company name; this will display only your products in the “Brand name” column (Column D).
  2. In the “MoH Drug Name” columns (column J), indicate for each of your products the identified list of drugs that may be written similarly to yours. 
  3. In the “MoH Drug Name” columns (column K) indicate for each of your products the identified list of drugs that may be pronounced similarly to yours. 
  4. For steps 3 and 4, please write NA If not applicable
  5. Fill the “Comment” column (Column L) with any information present that you may find relevant.
  6. Please refer to rows number 4, 5, and 6 as examples. These were extracted from the Institute for Safe Medications Practices List.
  7. Send us the filled excel sheet at the following email addresses: lasa.moph@gmail.com or lasa@moph.gov.lb
  8. Ensure that your file is named as follow: (name of the distributor-lasalist2023),Example: Mersaco-lasalist2023
 
You are kindly expected to reply back within 2 months after receiving this email (by May 31st, 2023), the latest.
 
Thank you for your time and cooperation.


Reminder,

Reference to previous communication related to the submission of the LASA (Look-Alike Sound-Alike) list, we would like to kindly remind all drug distributers and local manufacturers to complete the list by May 31st, 2023.

As per the previously shared instruction, the list must be filled out with utmost accuracy. It should be completed in accordance with the identified company's own LASA list. We stress the importance of adhering to these instructions to ensure the safety and efficacy of medication use.

In case there are no LASA products, please verify this by an email to lasa.moph@gmail.com.

We appreciate your cooperation in this matter.

Quality Assurance of Pharmaceutical Products Department
Lebanese National Pharmacovigilance Program
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ATC Name B/G Ingredients Dosage Form Price
R03AL01 ATROVENT COMP. HFA B Fenoterol Hydrobromide - 20mcg/actuation, Ipratropium bromide - 50mcg/actuation Inhalation aerosol metered dose 544,256 L.L
L01XX41 HALAVEN B Eribulin mesylate - 0.88mg/2ml 0.88mg/2ml Injectable solution L.L
A07EC02 SALOFALK B Mesalazine - 500mg 500mg Tablet, enteric coated 2,874,479 L.L
C09CA04 APROVEL B Irbesartan - 150mg 150mg Tablet, film coated 651,764 L.L
J07CA06 PENTAXIM B Poliomyelitis virus type 3 inactivated(Prefilled syringe) - 32D.U., Poliomyelitis virus type 2 inactivated(Prefilled syringe) - 8D.U., Poliomyelitis virus type 1 inactivated(Prefilled syringe) - 40D.U., Bordetella pertussis antigen (Prefilled syringe) - toxoid 25mcg+filamentous haemaglutinin 25mcg, Tetanus toxoid (Prefilled syringe) - ?40IU, Diphtheria toxoid (Prefilled syringe) - ?30IU, H. Influenza type b polysaccharide(Vial) - 10mcg Injectable dry powder+suspension 2,558,676 L.L
N05AD01 HALDOL B Haloperidol - 5mg 5mg Tablet 231,141 L.L
R03AL02 COMBIVENT B Salbutamol (sulfate) - 2.5mg/2.5ml, Ipratropium bromide - 500mcg/2.5ml Inhaltion solution with nebuliser 745,833 L.L
L01ED03 ALECENSA B Alectinib - 150mg 150mg Capsule, hard L.L
A10BK03 JARDIANCE B Empagliflozin - 25mg 25mg Tablet, film coated 3,081,923 L.L
J07CA09 INFANRIX HEXA B Diphteria toxoid purified (Prefilled syringe) - ?30IU/0.5ml, Tetanus toxoid purified (prefilled syringe) - ?40IU/0.5ml, Bordetella pertussis antigen (Prefilled syringe) - toxoid 25mcg+filamentous haemaglutinin 25mcg+pertactin 8mcg/0.5ml, Poliomyelitis virus type 1 antigen (prefilled syringe) - 40D.U./0.5ml, Poliomyelitis virus type 2 antigen(prefilled syringe) - 8D.U./0.5ml, Poliomyelitis virus type 3 antigen (prefilled syringe) - 32D.U./0.5ml, HBs Antigen (prefilled syringe) - 10mcg/0.5ml, H. Influenza type b polysaccharide (Vial) - 10mcg/0.5ml Injectable suspension 4,230,416 L.L
L01EX01 SUTENT B Sunitinib maleate - 50mg 50mg Capsule 197,706,574 L.L
S01AE03 CILOXAN B Ciprofloxacine (HCl) - 3mg/ml 3mg/ml Drops solution 348,055 L.L
A07EC02 ASACOL B Mesalazine - 800mg 800mg Tablet 6,833,439 L.L
N05AD01 HALDOL DECANOAS B Haloperidol (Decanoate) - 50mg/ml 50mg/ml Injectable solution 444,812 L.L
A07EC02 PENTASA B Mesalazine - 1g 1g Tablet, controlled release 4,945,340 L.L
D10AD03 DIFFERIN B Adapalene - 0.1g/100g 0.1% Cream 521,411 L.L
G04BE09 LEVITRA B Vardenafil (HCl) - 20mg 20mg Tablet, film coated 2,660,808 L.L
J07CA11 DIPHTHERIA, TETANUS,PERTUSSIS, HEPATITIS B AND HAEMOPHILUS INFLUENZAE TYPE B CONJUGATE VACCINE B Diphteria Toxoid1 - ?25Lf (?30IU)/0.5ml, Tetanus toxoid1 - ?2.5Lf (?40IU)/0.5ml, Bordetella pertussis (Whole cell) - ?16OU (?4.0IU)/0.5ml, HBs Antigen (r DNA)1 - ?10mcg/0.5ml, H. Influenza type b, purified capsular polysaccharide2 - 10mcg/0.5ml, 1 adsorbed on aluminium phosphate, Al+++ - ?1.25mg , 2 conjugated to tetanos toxoid carrier protein - Injectable suspension 1,515,854 L.L
R03AL03 ANORO ELLIPTA B Vilanterol - 25mcg, Umeclidinium bromide - 62.5mcg Inhalation powder 5,367,774 L.L
A10BK03 JARDIANCE B Empagliflozin - 10mg 10mg Tablet, film coated 3,081,923 L.L
L01AA01 ENDOXAN B Cyclophosphamide (monohydrate) - 500mg 500mg Injectable powder for solution 764,646 L.L
L01EX02 NEXAVAR B Sorafenib - 200mg 200mg Tablet, film coated 82,858,698 L.L
M01AH05 ARCOXIA B Etoricoxib - 90mg 90mg Tablet, film coated 2,119,240 L.L
R03AL04 ULTIBRO BREEZHALER B Indacaterol - 110mcg, Glycopyronium - 50mcg Capsule, inhalation 4,031,528 L.L
L01ED01 XALKORI B Crizotinib - 250mg 250mg Capsule L.L
A07EC02 SALOFALK B Mesalazine - 1000mg 1000mg Granules, gastro-resistant, prolonged release 3,874,298 L.L
D10AD03 DIFFERIN B Adapalene - 0.1g/100g 0.1% Gel 503,941 L.L
L01AA06 HOLOXAN B Ifosfamide - 1g 1g Injectable powder for solution 3,586,850 L.L
L01EX03 VOTRIENT B Pazopanib HCl - 400mg 400mg Tablet, film coated 77,725,025 L.L
L04AA37 OLUMIANT B Baricitinib - 2mg 2mg Tablet, film coated 68,053,864 L.L
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