Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
D10AD03	DIFADERM	G	Adapalene - 0.1%	0.1%	Gel	414,671 L.L
N06AX21	DULOXA 30	G	Duloxetine HCl - 30mg	30mg	Capsule, delayed release	716,716 L.L
B05CX01	DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	193,062 L.L
D10AD03	DIFADERM	G	Adapalene - 0.3%	0.3%	Gel	952,208 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
N06AX21	DULOXETINE BIOGARAN	G	Duloxetine HCl - 60mg	60mg	Capsule, gastro-resistant	573,821 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	158,587 L.L
N06AX21	DULOXETINE BIOGARAN	G	Duloxetine HCl - 30mg	30mg	Capsule, gastro-resistant	573,821 L.L
S01BA01	DEXAFREE	G	Dexamethasone Phosphate - 1mg/ml	1mg/ml	Drops solution	563,070 L.L
B05CX01	DEXTROSE INJECTION 5%	G	Dextrose, H2O - 5g/100ml		Injectable solution	212,797 L.L
S01BA01	DEXAFREE	G	Dexamethasone Phosphate - 1mg/ml	1mg/ml	Drops solution	563,070 L.L
C05AE03	DILTIGEL	G	Diltiazem HCl - 2%	2%	Gel	632,950 L.L
S01BC03	DICLOFTIL	G	Diclofenac sodium - 0.1%	0.1%	Drops solution	1,038,790 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	148,566 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	179,456 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	163,184 L.L
M01AX05	DONA	G	Glucosamine hemisulfate - 1500mg	1500mg	Powder for solution	1,615,299 L.L
B05CX01	DEXTROSE	G	Dextrose, H2O - 33g/100ml	33g/100ml	Injectable solution	287,295 L.L
S01CA01	DEXATOBRIN	G	Dexamethasone - 1mg/ml, Tobramycin - 3mg/ml		Drops suspension	239,204 L.L
B05CX01	DEXTROSE	G	Dextrose, H2O - 50g/100ml	50g/100ml	Injectable solution	329,815 L.L
B05CX01	DEXTROSE	G	Dextrose, H2O - 20g/100ml	20g/100ml	Injectable solution	807,874 L.L
A11CC03	DERIL	G	Alfacalcidol - 1mcg	1mcg	Capsule, soft	783,460 L.L
L01AX04	DACARBAZINE MEDAC	G	Dacarbazine - 200mg	200mg	Injectable powder for solution	15,866,076 L.L
L01AX04	DACARBAZINE MEDAC	G	Dacarbazine - 1,000mg	1,000mg	Injectable powder for solution	5,411,654 L.L
G04CA52	DUTAMSUVITAE	G	Tamsulosin HCl - 0.4mg, Dutasteride - 0.5mg		Capsule, hard	2,168,962 L.L
M02AA15	DICLOGESIC	G	Diclofenac sodium (diethylamine) - 10mg/g	1%	Gel	135,728 L.L
C05CA03	DIOSMINE BIOGARAN CONSEIL	G	Diosmin - 600mg	600mg	Tablet, coated	761,959 L.L
G04CA52	DUTASTERIDE/TAMSULOSINE ARROW	G	Tamsulosin HCl - 0.4mg, Dutasteride - 0.5mg		Capsule	1,337,123 L.L
A11CC05	D-ESTER	G	Vitamin D3 - 10000IU	10000IU	Capsule, soft gelatin	999,563 L.L