Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
C05BB02	AETHOXYSKLEROL	B	Polidocanol (Lauromacrogol 400) - 1%	1%	Injectable solution	1,732,213 L.L
C05BB02	AETHOXYSKLEROL	B	Polidocanol (Lauromacrogol 400) - 3%	3%	Injectable solution	2,576,146 L.L
L04AB04	ABRILADA	BioTech	Adalimumab - 40mg	40mg	Injectable solution	40,259,574 L.L
L04AB04	ABRILADA	BioTech	Adalimumab - 40mg	40mg	Injectable solution	40,259,574 L.L
L04AB04	ADALIREL	BioTech	Adalimumab - 40mg	40mg	Injectable solution	15,102,158 L.L
R03DA05	AMINOPHYLLINE RENAUDIN	G	Aminophylline - 250mg/10ml	2.5%	Injectable solution	739,113 L.L
A10AB01	ACTRAPID	BioTech	Insulin (human) - 100IU/ml	100IU/ml	Injectable solution	752,552 L.L
A10AB01	ACTRAPID	BioTech	Insulin (human) - 100IU/ml	100IU/ml	Injectable solution	752,552 L.L
L04AC07	ACTEMRA	BioTech	Tocilizumab - 162mg/0.9ml	162mg/0.9ml	Injectable solution	79,959,812 L.L
L01BC01	ALEXAN	G	Cytarabine - 100mg/5ml	100mg/5ml	Injectable solution	388,370 L.L
A10AB06	APIDRA SOLOSTAR	BioTech	Insulin glulisine - 100IU/ml	100IU/ml	Injectable solution	3,942,834 L.L
L01BC01	ALEXAN	G	Cytarabine - 1,000mg/20ml	1,000mg/20ml	Injectable solution	2,848,946 L.L
A10AB06	APIDRA	BioTech	Insulin glulisine - 100IU/ml	100IU/ml	Injectable solution	2,221,372 L.L
N02BG06	ACUPAN	B	Nefopam HCl - 20mg	20mg	Injectable solution	365,525 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 10,000IU	10000IU	Injectable solution	4,036,903 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 10,000IU	10,000IU	Injectable solution	10,661,285 L.L
N02CD01	AIMOVIG	BioTech	Erenumab - 70mg/ml	70mg/ml	Injectable solution	35,423,371 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 4000IU	4000IU	Injectable solution	8,728,144 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 4000IU	4000IU	Injectable solution	1,127,036 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 4000IU	4000IU	Injectable solution	4,748,244 L.L
B03XA01	ALPEEN	BioTech	Erythropoietin recombinant human (Epoetin alfa) - 40,000IU	40,000IU	Injectable solution	11,210,836 L.L
B05AA01	ALBUTEIN	BioHuman	Human Albumin - 20%	20%	Injectable solution	7,154,928 L.L
B05AA01	ALBUTEIN	BioHuman	Human Albumin - 20%		Injectable solution	4,031,528 L.L
A03BA01	ATROPINE	G	Atropine sulfate - 1mg/ml	1mg/ml	Injectable solution	702,149 L.L
A03BA01	ATROPINE SULFATE RENAUDIN	G	Atropine sulfate - 1mg/ml	0.1%	Injectable solution	397,777 L.L
A03BA01	ATROPINE I.V. 0.25 MG.	G	Atropine - 0.25mg/ml	0.25mg/ml	Injectable solution	2,412,129 L.L
A03BA01	ATROPINE	G	Atropine sulfate - 0.5mg/ml	0.5mg/ml	Injectable solution	680,315 L.L
A03BA01	ATROPINE SULFATE RENAUDIN	G	Atropine sulfate - 0.5mg/ml	0.5mg	Injectable solution	385,683 L.L
B05BA01	AMINOVEN 10%	B	Glacial Acetic Acid 99% - 5.297g/l, L-Proline - 15.0g/l, L-Alanine - 15.0g/l, Glycine - 14.0g/l, L-Histidine - 3.00g/l, L-Arginine - 12.0g/l, L-Valine - 6.20g/l, L-Tryptophan - 2.00g/l, L-Threonine - 4.40g/l, L-Phenylalanine - 5.10g/l, L-Methionine - 4.30g/l, L-Lysine (monoacetate) - 6.60g/l, L-Leucine - 7.40g/l, L-Isoleucine - 5.00g/l		Injectable solution	951,440 L.L
A03BA01	ATROPINE SULFATEAGUETTANT	G	Atropine - 0.1mg/ml	0.1mg/ml	Injectable solution	7,805,376 L.L