Rubella

Generalities
Agent	Rubella virus, genus Rubullovirus, family Togaviridae
Incubation period	14-17 days (range 14-21 days)
Period of transmissibility	- 7 days before rash and 4 days after rash onset - From congenital rubella: infants shed the virus for several months after birth
Reservoir	Humans
Modes of transmission	- Person-to-person: direct contact with droplets - Infants with Congenital Rubella Syndrome shed large quantities of virus in their pharyngeal secretions and urine. - Materno-foetal transmission: 90% of infants born to women infected with rubella during the 1st trimester. The risk of transmission is 10-20% by the 16th week, and rare after the 20th week.
Clinical presentation	- Febril maculo-papular rash - Complications: thrombocytopenia (1/3000), post-infectious encephalitis (1/6000), rarely chronic arthritis - Congenital Rubella Syndrome: Congenital malformation as deafness, cataracts, microphtalmia, congenital glaucoma, pigmentary retinopathy, nystagmus, microcephaly, meningo-encephalitis, mental retardation, patent ductus arteious, atrial or ventricular septal defects, other congenital heart disease, purpura, hepatosplenomegaly, jaundice, radiolucent bone disease
Resources
Case definitions	- MOPH circular no 12 (2013): Acquired Rubella - MOPH circular no 45 (2007): Congenital Rubella Syndrome
Forms	- Rash reporting form - CRS reporting form - Rash investigation form - CRS investigation form
Data	- Rubella 2021 - Rubella 2020 - Rubella 2019 - Rubella 2018 - Rubella 2017 - Rubella 2016 - Rubella 2015

ATC	Name	B/G	Ingredients	Dosage	Form	Price
L04AB02	REMSIMA SC	BioTech	Infliximab - 120mg/ml	120mg/ml	Injectable solution	52,597,003 L.L
N06BX06	SOMAZINA	B	Citicoline (sodium) - 1,000mg/4ml	1,000mg/4ml	Injectable solution	787,492 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
L04AB04	ABRILADA	BioTech	Adalimumab - 40mg	40mg	Injectable solution	40,259,574 L.L
B05CX01	DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	158,587 L.L
L04AB04	ABRILADA	BioTech	Adalimumab - 40mg	40mg	Injectable solution	40,259,574 L.L
N02BE01	PARACEROL	G	Paracetamol - 10mg/ml	10mg/ml	Injectable solution	1,536,012 L.L
B05CX01	DEXTROSE INJECTION 5%	G	Dextrose, H2O - 5g/100ml		Injectable solution	212,797 L.L
L04AB04	ADALIREL	BioTech	Adalimumab - 40mg	40mg	Injectable solution	15,102,158 L.L
N02BE01	SUPOFEN	G	Paracetamol - 10mg/ml	10mg/ml	Injectable solution	7,675,286 L.L
B05CX01	SERUFLEX DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
L01BA01	METHOTREXAT EBEWE	G	Methotrexate - 500mg	500mg	Injectable solution	1,842,408 L.L
L04AB04	CINNORA	BioTech	Adalimumab - 40mg/0.8ml	40mg/0.8ml	Injectable solution	14,817,734 L.L
B05CX01	SERUFLEX DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	158,587 L.L
L01BA01	EBETREXAT	G	Methotrexate - 50mg/5ml	50mg/5ml	Injectable solution	1,507,821 L.L
L04AB04	HUMIRA	BioTech	Adalimumab - 40mg/0.4ml	40mg/0.4ml	Injectable solution	33,860,031 L.L
B05CX01	SERUFLEX DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	171,228 L.L
L04AB04	HYRIMOZ	BioTech	Adalimumab - 40mg	40mg	Injectable solution	27,521,893 L.L
B05CX01	SERUFLEX DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	193,062 L.L
L04AB04	HYRIMOZ	BioTech	Adalimumab - 40mg	40mg	Injectable solution	27,521,893 L.L
B05CX01	SOLUFLEX DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	186,167 L.L
L01FC01	DARZALEX	BioTech	Daratumumab - 1800mg	1800mg	Injectable solution	494,909,963 L.L
L04AB06	SIMPONI	BioTech	Golimumab - 50mg/0.5ml	50mg/0.5ml	Injectable solution	72,719,241 L.L
B05CX01	SOLUFLEX DEXTROSE 5% INJECTION USP	G	Glucose - 5%	5%	Injectable solution	186,167 L.L
L04AB06	SIMPONI	BioTech	Golimumab - 100mg/1ml	100mg/1ml	Injectable solution	72,719,241 L.L
B05CX01	SOLUFLEX DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	205,703 L.L
B05CX01	SOLUFLEX DEXTROSE 5% INJECTION, USP	G	Glucose - 5%	5%	Injectable solution	221,792 L.L
L04AC05	STELARA	BioTech	Ustekinumab - 45mg	45mg	Injectable solution	151,777,679 L.L
M03AC09	ESMERON	B	Rocuronium bromide - 50mg/5ml	50mg/5ml	Injectable solution	4,949,372 L.L
B05CX01	DEXTROSE 7.5% INJECTION USP	G	Glucose - 7.5%	7.5%	Injectable solution	148,566 L.L