Meningococcal Infection

Generalities
Agent	Bacteria: Neisseria meningitidis (meningococcus), Gram negative diplococci - 12 serogroups have been identified - Six serogrouprs are responsible of invasive infection: A, B, C, W135, X, and Y.
Incubation period	2-10 days, commonly 3-4 days
Period of transmissibility	Cases should be considered infectious from exposure until 24 hours after starting treatment of prophylaxis with appropriate antibiotics with substantial concentrations in oro/nasopharyngeal secretions
Reservoir	- Humans - Asymptomatic carriage in nasopharynx is common.
Modes of transmission	- Person-to-person transmission by direct contact with respiratory droplets of infected people - Most cases acquired through exposure to asymptomatic carriers
Clinical presentation	- Bacterial meningitis - Septicaemia: rare ans severe with purpura - Complications: cerebral lesions, hearing loss, learning disorders among 10-20% of survivors - Case fatality: 8-15% despite treatment
Resources
Case definition	- MOPH circular no. 63 (2007) - MOPH circular no. 72 (2003): contacts
Forms	- Meningitis reporting form - Meningitis investigation form
Data	- Weekly report

ATC	Name	B/G	Ingredients	Dosage	Form	Price
J05AB01	CYCLOVEX	G	Aciclovir - 400mg	400mg	Tablet, scored	2,687,685 L.L
L01CD02	DOCETAXEL EBEWE	G	Docetaxel - 80mg/8ml	80mg/8ml	Injectable solution	19,518,281 L.L
L01XA03	OXALTIE	G	Oxaliplatin - 50mg	50mg	Injectable lyophilised powder for solution	2,957,797 L.L
L04AX04	LENOMA	G	Lenalidomide - 15mg	15mg	Capsule, hard	15,241,884 L.L
N03AG01	CONVULEX	G	Sodium Valproate - 300mg/ml	300mg/ml	Solution	1,018,633 L.L
N05AX08	RISCHOTIC OD 3	G	Risperidone - 3mg	3mg	Tablet, orally disintegrating	605,369 L.L
S02AA15	CETRAXAL OTICO	G	Ciprofloxacine (HCl) - 3mg/ml	3mg/ml	Drops	821,088 L.L
A10BB12	DIAMERIL	G	Glimepiride - 4mg	4mg	Tablet	322,522 L.L
B05BB01	SERUFLEX RINGER'S INJECTION, USP	G	Calcium chloride, 2H2O - 0.33g/l, Potassium chloride - 0.3g/l, Sodium chloride - 8.6g/l		Injectable solution	204,554 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LM	G	Potassium chloride - K+:2.00 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.75 mmol/l, Sodium acetate - Cl-:112 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C08CA01	LOWRAC 5	G	Amlodipine (besylate) - 5mg	5mg	Capsule	362,837 L.L
C09DB06	LOSANET AM	G	Losartan potassium - 100mg, Amlodipine - 5mg		Tablet	1,044,358 L.L
D03AX	HEALIN B	G	?-sitosterol - 0.25%	0.25%	Ointment	849,820 L.L
G03CA03	OESTRACLIN	G	Estradiol - 0.6mg/g	0.6mg/g	Gel	448,843 L.L
J01DE01	CEFIPEX 500 BENTA	G	Cefepime (hydrochloride) - 500mg	500mg	Injectable solution	545,216 L.L
J05AB01	VICLORIX 400	G	Aciclovir - 400mg	400mg	Tablet	3,589,851 L.L
L01CD02	DOCETAXEL GP PHARM	G	Docetaxel - 40mg/ml	80mg/2ml	Injectable concentrated solution+diluent	16,777,239 L.L
L01XA03	OXALTIE	G	Oxaliplatin - 50mg	50mg	Injectable lyophilised powder	2,957,797 L.L
L04AX04	LIDAMID 15	G	Lenalidomide - 15mg	15mg	Capsule	79,238,426 L.L
M05BA04	APO-ALENDRONATE	G	Alendronate (monosodium trihydrate) - 70mg	70mg	Tablet	1,173,175 L.L
N05AX08	RISCHOTIC OD 4	G	Risperidone - 4mg	4mg	Tablet, orally disintegrating	605,369 L.L
N07CA01	ALVIGO	G	Betahistine dihydrochloride - 16mg	16mg	Tablet, scored	1,204,339 L.L
R05CB01	TREBON N	G	Acetylcysteine - 600mg	600mg	Granules for suspension	596,666 L.L
A10BB12	GLIM	G	Glimepiride - 4mg	4mg	Tablet	628,918 L.L
B05BB01	SOLUFLEX RINGER'S INJECTION, USP	G	Calcium chloride, 2H2O - 0.33g/l, Potassium chloride - 0.3g/l, Sodium chloride - 8.6g/l		Injectable solution	221,792 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS	G	Potassium chloride - K+:1.5 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.75 mmol/l, Sodium acetate - Cl-:111.5 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C08CA01	LUSTRA	G	Amlodipine - 5mg	5mg	Tablet	485,127 L.L
C09DB07	CANDAM	G	Candesartan cilexetil - 8mg, Amlodipine - 5mg		Capsule, hard	1,376,095 L.L
D03AX	RENEBO	G	?-sitosterol - 0.25% w/w	0.25% w/w	Ointment	456,906 L.L
J01DE01	CEFEPIME LDP LABORATORIOS TORLAN	G	Cefepime - 1g	1g	Injectable powder for solution	5,933,065 L.L