Meningococcal Infection

Generalities
Agent	Bacteria: Neisseria meningitidis (meningococcus), Gram negative diplococci - 12 serogroups have been identified - Six serogrouprs are responsible of invasive infection: A, B, C, W135, X, and Y.
Incubation period	2-10 days, commonly 3-4 days
Period of transmissibility	Cases should be considered infectious from exposure until 24 hours after starting treatment of prophylaxis with appropriate antibiotics with substantial concentrations in oro/nasopharyngeal secretions
Reservoir	- Humans - Asymptomatic carriage in nasopharynx is common.
Modes of transmission	- Person-to-person transmission by direct contact with respiratory droplets of infected people - Most cases acquired through exposure to asymptomatic carriers
Clinical presentation	- Bacterial meningitis - Septicaemia: rare ans severe with purpura - Complications: cerebral lesions, hearing loss, learning disorders among 10-20% of survivors - Case fatality: 8-15% despite treatment
Resources
Case definition	- MOPH circular no. 63 (2007) - MOPH circular no. 72 (2003): contacts
Forms	- Meningitis reporting form - Meningitis investigation form
Data	- Weekly report

ATC	Name	B/G	Ingredients	Dosage	Form	Price
J05AB01	VICLORIX 800	G	Aciclovir - 800mg	800mg	Tablet	4,321,797 L.L
L01CD02	DOCETAXEL SPC	G	Docetaxel - 80mg/4ml	80mg/4ml	Injectable concentrate for solution	16,906,027 L.L
L04AX04	SOTIRA	G	Lenalidomide - 15mg	15mg	Capsule	76,208,289 L.L
M05BA04	MARVIL 70	G	Alendronate (monosodium trihydrate) - 70mg	70mg	Tablet, coated	1,173,175 L.L
N05AX12	ABIPREX 10	G	Aripiprazole - 10mg	10mg	Tablet	1,075,074 L.L
N07CA01	BETAHISTINE ARROW	G	Betahistine dihydrochloride - 16mg	16mg	Tablet	362,837 L.L
S02AA16	OFLOMED	G	Ofloxacin - 3mg/ml	3mg/ml	Drops solution	317,403 L.L
A03FA07	GAROPRIDE	G	Itopride Hydrochloride - 50mg	50mg	Tablet, film coated	213,671 L.L
A10BB12	GLUMYL 4	G	Glimepiride - 4mg	4mg	Tablet	317,403 L.L
B05BB02	5% DEXTROSE 0.9% SODIUM CHLORIDE INJECTION	G	Dextrose,H2O - 5g/100ml, Sodium chloride - 0.9g/100ml		Injectable solution	180,421 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS2	G	Potassium chloride - K+:1.5 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.5 mmol/l, Sodium acetate - Cl-:111 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C08CA01	TORANS	G	Amlodipine (besylate) - 5mg	5mg	Tablet	518,339 L.L
C09DB07	CORONOPINE	G	Candesartan cilexetil - 8mg, Amlodipine - 5mg		Capsule, hard	1,368,032 L.L
G03CA03	VAGIFEM	G	Estradiol (hemihydrate) - 10mcg	10mcg	Tablet	2,254,968 L.L
H02B	PREDALONE PLUS	G	Prednisolone sodium phosphate - 10mg/5ml, Dexchlorpheniramine maleate - 2mg/5ml		Syrup	890,776 L.L
J01DE01	CEFEPIME PANPHARMA	G	Cefepime - 1g	1g	Injectable powder for solution	5,933,065 L.L
L01XG01	ALVOCADE	G	Bortezomib - 3.5mg	3.5mg	Injectable powder for solution	14,169,600 L.L
M05BA04	OREK	G	Alendronate - 70mg	70mg	Tablet, coated	2,404,838 L.L
N05AX12	ATYPRAL	G	Aripiprazole - 10mg	10mg	Tablet	712,237 L.L
N07CA01	VASOSERC FORTE	G	Betahistine dihydrochloride - 16mg	16mg	Tablet	944,529 L.L
R05CB02	BROMHEXINE	G	Bromhexine - 4mg/5ml	4mg/5ml	Elixir	176,619 L.L
A03FA08	CINITREX	G	Cinitapride - 1mg	1mg	Tablet	636,981 L.L
A10BB12	GLYPRIDE	G	Glimepiride - 4mg	4mg	Tablet	657,139 L.L
B05BB02	5% DEXTROSE 0.9% SODIUM CHLORIDE INJECTION	G	Dextrose,H2O - 5g/100ml, Sodium chloride - 0.9g/100ml		Injectable solution	226,388 L.L
B05ZA	CONCENTRATE SOLUTION FOR HEMODIALYSIS LS3	G	Potassium chloride - K+:2.00 mmol/l, Magnesium chloride - Mg++:0.75 mmol/l, Calcium chloride - Ca++:1.60 mmol/l, Sodium acetate - Cl-:112 mmol/l, Sodium chloride - Na+:140 mmol/l		Injectable solution	L.L
C08CA01	AMLINE	G	Amlodipine - 10mg	10mg	Tablet	662,962 L.L
C09DB07	CANDAM	G	Candesartan cilexetil - 16mg, Amlodipine - 5mg		Capsule, hard	1,376,095 L.L
D03BA	SERODASE	G	Serratiopeptidase - 5mg	5mg	Tablet, enteric coated	460,938 L.L
G03CA03	MONTADIOL	G	Estradiol - 0.01%	0.01%	Cream	1,105,982 L.L
J01DE01	CEFIPEX 1000 BENTA	G	Cefepime - 1,000mg	1,000mg	Injectable dry powder+diluent	703,918 L.L